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目的 调查老年癌症患者认知衰弱(cognitive frailty, CF)现状，并分析其影响因素。方法 采用便利抽样法，选取2023年11月—2024年5月南通大学附属医院肿瘤科4个肿瘤病区的308例老年癌症患者作为研究对象，采用一般资料问卷、日常生活活动能力量表(activities of daily living, ADL)、简易营养评估量表(mini nutrition assessment-shortform, MNA-SF)、老年抑郁评定量表(geriatric depression scale, GDS-15)、匹兹堡睡眠质量指数量表(pittsburgh sleep quality index, PSQI)、Fried衰弱量表及简易精神状态量表(mini-mental state examination, MMSE)进行调查，并对相关数据进行分析。结果 老年癌症CF发生率为26.6%;二元logistic回归分析结果显示：性别、文化程度、人均月收入、日常活动能力、营养不良、抑郁及睡眠障碍是老年癌症患者CF的影响因素(均P<0.05);相关性分析结果显示：老年癌症患者CF与抑郁、营养不良、睡眠障碍及日常活动能力受损均呈正相关(r=0.296、0.455、0.445、0.363,均P<0.01)。结论 老年癌症患者CF的发生率较高，提示医护人员应重视该类患者认知功能和衰弱的评估，并尽早对高危人群采取针对性干预措施，以降低患者CF的风险。
Abstract：Objective To investigate the current status of cognitive frailty(CF) in elderly cancer patients and analyze its influencing factors. Methods Using a convenience sampling method, 308 elderly cancer patients from 4 oncology wards of the Affiliated Hospital of Nantong University between November 2023 and May 2024 were selected as the research subjects, and were investigated by a general information questionnaire, the activities of daily living scale(ADL), the mini nutritional assessment-short form(MNA-SF), the geriatric depression scale(GDS-15), the Pittsburgh sleep quality index(PSQI), the Fried frailty scale, and the mini-mental state examination(MMSE),and the relevant data was analyzed.Results The incidence of CF among elderly cancer patients was 26.6%. The results of binary logistic regression analysis showed that female gender, education level, monthly income, impaired activities of daily living, malnutrition, depression, and sleep disorders were significant influencing factors(all P<0.05). Correlation analysis indicated that CF was positively correlated with depression, malnutrition, sleep disorders, and impaired activities of daily living(r=0.296, 0.455, 0.445, 0.363; all P<0.01). Conclusion The incidence of CF is relatively high among elderly cancer patients. Healthcare providers should prioritize the assessment of cognitive function and frailty in this population and implement targeted intervention measures for high-risk groups as early as possible to reduce the risk of CF.
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基本信息:
DOI：10.16821/j.cnki.hsjx.2025.23.002
中图分类号:R473.73
引用信息:
[1]王慧,吴玉霞,董苏云,等.老年癌症患者认知衰弱现状及影响因素分析[J].护士进修杂志,2025,40(23):2472-2478.DOI:10.16821/j.cnki.hsjx.2025.23.002.
基金信息:
江苏省医院协会医院管理创新研究课题(编号：JSYGY-2023-168)